Poster Program

Poster session one

[P1.1]

In silico molecular modification and synthesis of 2- substituted quinazoline-4(3H)-one for anti-inflammatory and analgesic activity
S. Sree Kumar*, P. Jayasekhar; College of Pharmaceutical Sciences, India

[P1.2]

Design and synthesis of some novel n-benzylidine-4, 6-diaryl-pyrimidin-2-amine derivatives
A. Hasan*, M. Khaleeq, U. Riaz; Quaid-i-Azam University, Pakistan

[P1.3]

Withdrawn

[P1.4]

High stereoselectivity in chelation-controlled intermolecular Heck reactions of cyclic enol ether with organic chlorides
G.K. Datta*, M. Larhed; Uppsala University, Sweden

[P1.5]

Synthesis and study of new [1,4]-diazepines and [1,4]- oksazepines
H. Ibrahimi*, V. Vrajolli, S. Govori, O. Leci, V. Kalaj, A. Rifati; University of Prishtina, Kosovo

[P1.6]

Desulfitative carbon-carbon cross-coupling of thioamide fragments with boronic acids
H. Prokopcova*, C.O. Kappe; Karl-Franzens-University, Austria

[P1.7]

Diethyl bromodifluoromethylphosphonate: A highly efficient, environmentally benign and commercially available difluorocarbene precursor
Y. Zafrani, Y. Segall*; Israel Institute for Biological Research, Israel

[P1.8]

Synthetic routes to heterocyclic alpha-aminophosphonic acids: Building blocks for phosphorus containing peptides
N. Rabasso*, N. Louaisil, A. Fadel; Université Paris-Sud XI, France

[P1.9]

The first synthesis of bryoanthrathiophene, a novel angiogenesis inhibitor from the Bryozoan Watersipora Subtorquata
X.D. Zhou*, R.X. Qin, S.L. Luo; The Third Military Medical University, China

[P1.10]

Total synthesis of apratoxin A
Y. Numajiri*, T. Doi, T. Takahashi; Tokyo Institute of Technology, Japan

[P1.11]

5-hydroxyindoles and 3-hydroxy-2,5-dihydro-1H-pyrroles with high density of functional groups: Synthesis using a novel method for Lewis acid catalyzed nenitzescu reaction and a novel one-step reaction for obtaining dihydropyrroles by interaction of C-aryl1-N-aryl2-nitrones with sodium malonate
V.S. Velezheva*, A.N. Konovalov, A.I. Sokolov, E.N. Rodlovskaya;  A. N. Nesmeyanov Institute of Organoelement Compounds, Russia

[P1.12]

Acyloins from Morita-Baylis-Hillman adducts: An alternative approach for the total synthesis of bupropion
G.W. Amarante*, M. Cavallaro, P. Rezende, F. Coelho; Campinas State University, Brazil

[P1.13]

Synthesis of azepino[4,5-b]indolones featuring a radical oxidative aromatic substitution
P.E. Reyes-Gutierrez*, R. Martinez, L.D. Miranda; Universidad Nacional Autonoma de Mexico, Mexico

[P1.14]

Synthesis of bicyclic N-sulfonylamidines through Ritter type reaction on carene and pinene derivatives
V. Ganesh*, D. Sureshkumar, S. Chandrasekaran;  Indian Institute of Science, India

[P1.15]

Intra-annular Savige-Fontana reaction: One step conversion of synthetic phakellistatinoids to amatoxinoids
J.P. May, D.M. Perrin*; University of British Columbia, Canada

[P1.16]

5-substituted 2,4-dioxopiperidines: Synthesis and useful applications
A. Maccario, R. D'Alessio, M. Menichincheri, P. Orsini*, A. Scolaro, E. Vanotti;  Nerviano Medical Sciences, Italy

[P1.17]

Catalytic asymmetric cyclopropanation of alkenes with diazoesters catalyzed by chiral phenyloxazolinyl (Pheox) ruthenium (II) complexes
K.P. Phomkeona*, T.T. Takemoto, S.I. Iwasa; Toyohashi University of Technology, Japan

[P1.18]

Synthesis and self-assembly of dendritic dipeptide pores
S. Nummelin*¹,², V. Percec¹, A.E. Dulcey¹, M. Peterca¹, J. Smidrkal¹, P.A. Heiney¹;  ¹University of Pennsylvania, USA, ²Helsinki University of Technology, Finland

[P1.19]

Phosphonium ionic liquids as solvents for the diels-alder reaction
J. Yu*, N. Karodia;  University of Bradford, UK

[P1.20]

Extensive bioisosteric approach to design of improved anticancer agents
S.O. Awofisayo*¹, O.A. Awofisayo¹, O.E. Akpan²; ¹University of Uyo, Nigeria, ²JDJIDE Pharma Limited, Nigeria

[P1.21]

Synthesis of isolable beta,beta-difluoro-alpha-phenyl(methyl)vinylstannanes and their cross-coupling reactions
J.H. Jeong, J.H. Choi, J.A. Cho*; Yonsei University, South Korea

[P1.22]

From matricaria esters to ladderanes: Synthesis inspired by nature
S. Garrais*, W. Goldring; Queen's University Belfast, UK

[P1.23]

Towards the total synthesis of trichodermamide A
J.R. Donald*, R.J.K. Taylor; University of York, UK

[P1.24]

Synthesis of a-(benzotriazol-1-yloxy)-ketones and a-(benzotriazol-1-yloxy)-substituted carboxylic esters as potential synthons in new drugs development
B.K. Pchelka*, A. Petit; Universite de Paris Sud XI, France

[P1.25]

Benzisoselenazol-3(2H)-ones as potential antiviral agents: Synthesis and structure-activity relationship
M. Pietka-Ottlik*¹, K. Kloc¹, K. Kolodziejczyk¹, E. Piasecki¹,², J. Mlochowski¹;  ¹Institute of Organic Chemistry, Wroclaw University of Technology, Poland, ²Polish Academy of Sciences, Poland

[P1.26]

Small-molecule oligosaccharide tags for derivatization of glycan libraries
N. Chindarkar*, A.H. Franz;  University of the Pacific, USA

[P1.27]

Synthesis and application of chiral ligands with perfluoroalkyl carbinol moiety directed towards asymmetric synthesis; especially useful for addition of dimethylzinc to aldehydes
I. Kumadaki*, A. Ando, Y.S. Sokeirik, K. Sato, A. Tarui, M. Omote;  Setsunan University, Japan

[P1.28]

A novel combined reagent of Cl3CCONH2/PPh3 for the synthesis of bioactive esters
O. Chantarasriwong¹, W. Chavasiri*¹, D.O. Jang²;  ¹Chulalongkorn University, Thailand, ²Yonsei University, South Korea

[P1.29]

Withdrawn

[P1.30]

Synthesis of peptide nucleic acid analogs using click chemistry
B.J. McNelis*, R. Thomas, G. Stettler, C. Donohoe, D. Lough; Santa Clara University, USA

[P1.31]

One-pot procedure for the synthesis of new polydentate ligands by the Aza-Wittig reaction
A. Fernández*, G. Blanco, C. Peinador, J.M. Quintela;  University of A Coruña, Spain

[P1.32]

Thiol-reactive photo-switches for manipulating protein conformation: Design, synthesis, and evaluation
A. Woolley*, A. Beharry, F. Zhang, L. Chi, O. Sadovski; University of Toronto, Canada

[P1.33]

cDNA microarray studies on (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line
J. M. Campos*¹, M. Díaz-Gavilán¹, F. Rodríguez-Serrano¹, J. A. Marchal¹, O. Caba², A. Aránega¹, M.A. Gallo¹, A. Espinosa¹;  ¹University of Granada, Spain, ²University of Jaen, Spain

[P1.34]

New targeting systems for polymeric conjugates of amphotericin B
M. Sedlak*, P. Drabina, P. Bajerova, K. Ventura;  University of Pardubice, Czech Republic

[P1.35]

Synthesis of apicularen A and related salicylic acid macrolide structures as novel antiangiogenic compounds against cancer
J.S.S. Rountree*, P.V. Murphy; University College Dublin, Ireland

[P1.36]

Design, synthesis and biological evaluations of tubulin polymerization promoted D-seco paclitaxel analogs with and without cytotoxicity
C.-G. Yang¹,², S.-R. Wang¹,², Y. Zhao¹,², I. Barasoain³, J. F. Diaz³, W.-S. Fang *¹; ¹CAMS, China, ²Ministry of Education of P.R. China, China, ³CSIC, Spain

[P1.37]

Synthesis and biological evaluation of novel fluorinated pyrazolone nucleosides as anti-tumor agents
I. Abdou*, S. Merghani, H. Zohdi, A. Al-Marzouqi; UAE University, United Arab Emirates

[P1.38]

Novel tetracycline derivatives as highly selective tools for the control of gene expression
S. Lochner, J. Einsiedel*, C. Berens, L. Drueppel, W. Hillen, P. Gmeiner; Friedrich Alexander University, Germany

[P1.39]

Control in a equilibrium network based on self-assembling a,g-cyclic peptides
M.J. Perez-Alvite*¹, L. Castedo¹, J.R. Granja¹,  ¹Universidad de Santiago de Compostela, Spain

[P1.40]

Influence of side chain length and functionality of C-linked antifreeze glycoproteins on recrystallization-inhibition
R.Y. Tam, R.N. Ben*; University of Ottawa, Canada

[P1.41]

Glycosyl iodides: A powerful tool for the efficient syntheses of glycolipids
S.S. Kulkarni, M. Schombs, W. Du, J. Gervay-Hague, R.A. Davies*;  University of California at Davis, USA

[P1.42]

Synthesis of substituted 3-(4-nitrophenyl) triazoles as antiasthmatic agents
S. Kaur*¹, G. Bansal², G. Singh³;  ¹ISF College of Pharmaceutical Sciences and Drug Research, India, ²Punjabi University, India, ³Pt B.D. Sharma Post Graduate Institute of Medical Sciences, India

[P1.43]

Chemical ligation of epoxide-containing fusicoccins and peptide fragments induced by 14-3-3 protein surface
J. Ohkanda*, T. Maki, A. Kawamura, N. Kato; Osaka University, Japan

[P1.44]

Densitometric determination azithromycin injection of in pharmaceutical preparation by HPLC assay method development and their method validation
T. Barot*, P. Patel; M.G.Sciences Institute, India

[P1.45]

Synthesis of novel 2-pyridone analogs for treatment of convulsive seizures
M. Ismail*¹, A. El-Sayed¹, D. Abou El Ella²;  ¹Al-Azhar University, Egypt, ²Ain Shams University, Egypt

[P1.46]

Chemical synthesis and biological characterization of structural analogues of the CAI-1 autoinducer of Vibrio cholerae
M.F. Semmelhack¹, M.E. Pomianek*¹, C.M. Kraml¹, D.A. Higgins¹, B.L. Bassler²;  ¹Princeton University, USA, ²Howard Hughes Medical Institute, USA

[P1.47]

Substituted phenanthrene imidazoles as potent and selective mPGES-1 inhibitors
A. Giroux*, B. Cote, C. Brideau, J. Mancini, D. Riendeau, R. Friesen;  Merck Frosst, Canada

[P1.48]

Design and synthesis of 2-(-3-benzoylphenyl) propanoic acid, analogues and ester prodrug
M. Ahmed*, H. Al.Awag, M. Aboshaala, M. Salama*; University of Garyounis, Libya

[P1.49]

Hypoxia-selective DNA alkylating agents: Substituent effects on the properties of nitro seco 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (nitroCBI) prodrugs
M. Tercel*, F.B. Pruijn, G.J. Atwell, S. Yang, R.J. Stevenson, M.Boyd, et al.; Auckland Cancer Society Research Centre, New Zealand

[P1.50]

Design, synthesis and cytotoxic evaluation of some 6H-indolo [2,3-B] quinoxaline derivatives
N.S.H Narayana Moorthy*, C. Karthikeyan, P. Trivedi; Rajiv Gandhi Technical University, India

[P1.51]

Discovery and optimization of a new series of potent and selective inhibitors of the c-met kinase
J.W. Lohman; Amgen Inc, USA

[P1.52]

2D quantitative structure activity relationship of piperazinyl phenylalanine derivatives as VLA-4/VCAM-1 inhibitors
D. Bhargava*, C. Karthikeyan, P. Trivedi, H.N. Moorthy; Rajiv Gandhi Technical University, India

[P1.53]

Synthesis, characterization and biological evaluation of novel fluoxetine analogues as selective serotonin reuptake inhibitors
N. Kawathekar*, P. Pandey, J. Patel;  Shri. G. S. Institute of Technology and Science, India

[P1.54]

Synthesis and properties of a novel zinc phthalocyanine conjugated to serum albumin
C.S. Gonçalves, M.A.G. Cardoso*, M. Beltrame Jr;  University of Vale do Paraiba, Brazil

[P1.55]

Identification of inhibitors of angiogenetic enzyme targets by high-throughput docking and medicinal chemistry
K. Lafleur*, D. Huang, C. Nevado, A. Caflisch; University of Zürich, Switzerland

[P1.56]

Synthesis of 4-amino-5-aryl-1, 2, 4-triazole-3-thiones and 2, 5 disubstituted 1, 3, 4-oxadiazole and their pharmacological screening for antibacterial anticancer and anti HIV activity
R.A. Fursule*¹, R.L. Bakal¹, A.M. Manikrao²; ¹H. R. Patel Women's College of Pharmacy, India, ²SGSPS Institute of Pharmacy, India

[P1.57]

Specific fixed aqueous layer of three-component hybrid liposomes related to inhibition of hepatoma cells growth
Y. Matsumoto*, Y. Tanaka, K. Goto, R. Ueoka; Sojo University, Japan

[P1.58]
NEW

A traceless sulfone linker in solid-phase organic synthesis: Preparation of polyisoprenoid alcohols and their derivatives
Y-F Chang*, W-Cheng; Academia Sinica, Taiwan

[P1.59]

Synthesis of analogues of the marine natural product squalamine
P. Brockbank*, J. Mann; Queen's University Belfast, UK

[P1.60]

Synthesis and biological evaluation of some metal (copper) coordination complexes
S.K. Bharti, H.N. Moorthy*; School of Pharmaceutical Sciences, India

[P1.61]

Synthesis of new fluoroketone phospholipase A2 inhibitors as novel agents for the treatment of multiple sclerosis
V. Constantinou-Kokotou*³, C. Baskakis¹, V. Magrioti¹, C.G. Kokotos¹, A. Kalyvas², D. Stephens³, G. Kokotos¹;  ¹University of Athens, Greece, ²McGill University, Canada, ³University of California San Diego, USA, ⁴Agricultural University of Athens, Greece

[P1.62]

Design, synthesis and pro-kinetic activity of novel anilinocarbonyl arylvinylbenzamides
S.C. Khadse*¹, R.R. Patil¹, V.A. Chatpalliwar¹, G.S. Talele², R.A. Fursule¹; ¹R. C. Patel College of Pharmacy, India, ²J. Z. M. D. Society’s College of Pharmacy, India

[P1.63]

Rapid synthesis of seven-membered sugar ring nucleoside analogues
J.C. Meillon*, T. Bouisset, S. Cappelle, D. Chaves, A. Damont, D. Dukhan; Idenix Pharmaceuticals, France

[P1.64]

Targeted and selective delivery of multiple pharmacological agents as a strategy for anti-parasitic chemotherapy
S.S. Mahajan, V. Newman, J.L. DeRisi, A.R. Renslo*; University of California at San Francisco, USA

[P1.65]

Design and synthesis of nucleotide analogs as potential inhibitors for glycosyltransferases
U. Sahni*, J. H. Wong, X. Chen, J. Gervay-Hague; University of California at Davis, USA

[P1.66]

Community-based approach to research on infectious diseases of the developing world and global health
B. Bunin*, M. Hohman, S. Ernst, K. Gregory; Collaborative Drug Discovery, USA

[P1.67]

Computational DFT studies of the Pd(II)-catalyzed aldehyde allylation reaction: Mechanism and chemoselectivity
F. Pichierri*, Y. Yamamoto; Tohoku University, Japan

[P1.68]

Modeling and simulation: Density, molar volume and apparent molar volume behavior of hydroxamic acid
A. Pande*, R. Pande, P. Chaudhari;  NIT RAIPUR, India

[P1.69]

A molecular dynamics study of paclitaxel binding to human serum albumin
I. Stoica¹, K. Paal*²,  ¹University College London, UK, ²University of Ontario Institute of Technology, Canada

[P1.70]

Withdrawn

[P1.71]

Synthesis and characterization of novel, self-aggregating porphyrin-peptide assemblies
M.E. Chavez*, H. Kim, S. Van Name, A. Eldrede-Martin, K. Åkerfeldt; Haverford College, USA

[P1.72]

Preparation of iridescent-reflective polymers by asymmetric electrochemical polymerization, and grating function
H. Yoneyama, K. Kawabata*, A. Tsujimoto, H. Goto; University of Tsukuba, Japan

[P1.73]

Preparation of furan-based optically active conjugated polymers by asymmetric electrochemical polymerization
K. Kawabata*, H. Yoneyama, H. Goto; University of Tsukuba, Japan

[P1.74]

Preparation of optically active polythiophene derivatives from achiral monomers in cholesteric liquid crystals
F. Togashi, R. Ohta*, H. Goto; University of Tsukuba, Japan

[P1.75]

Synthesis and application of an array of pyridine derivatives from electrophilic attack on C and N centres for development of agrochemicals
A.M. Bello*¹, S.O. Awofisayo², O.A. Awofisayo²;  ¹JDJIDE Pharmaceuticals Limited, Nigeria, ²University of Uyo, Nigeria

[P1.76]

Synthesis of highly substituted imidazo[1,5-a]pyrazines by 3-cr/2-cr sequence
A. Shaabani, A. Maleki*, H. Mofakham; Shahid Beheshti University, Iran

[P1.77]

Anti-microbial activity - essencial oil of rosmarinus officinalis, obtained by steam drag and supercritical carbon dioxide methods
M.A.A. Pereira*, E. Cassel, D. Milão;  Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Brazil

[P1.78]

The one-pot, three component synthesis of functionalized 2-aminofurfuryl derivatives
M. Asnaashari Isfahani*, J. Taheri, S. Shaikhy; Islamic Azad University, Iran

[P1.79]

Aripiprazol – a modern anti-psychotic drug: Impurities formed during synthesis and their elimination
L. Hejtmankova*, P. Lustig;  Zentiva a.s., Czech Republic

[P1.80]

Synthesis of 4-methylcoumarins and comparative Specificities of substituted acetoxy and propoxy derivatives for acetoxy drug: Protein transacetylase
Y.K. Tyagi*¹, S. Arora², R.K. Gupta¹, H.G. Raj²;  ¹GGSIP University, India, ²Vallabhbhai Patel Chest Institute, University of Delhi, India

[P1.81]

Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems
S.H. Chan¹, K.H. Lam¹, L. Xu¹, Q Fan², A.S.C. Chan¹; ¹Hong Kong Polytechnic University, Hong Kong, ²Chinese Academy of Sciences, China

[P1.82]

Total synthesis of norbadione A
T. Le Gall*, Y. Bourdreux, S. Nowaczyk, C. Billaud, A. Mallinger, C. Willis;  CEA, France

[P1.83]

General methods for flash chromatography using disposable columns
W.C. Stevens Jr.¹, S.A. Ellis*², D.C. Hill³; ¹Exelixis Inc, USA, ²Thomson Instruction Company, USA, ³AstraZeneca Pharmaceuticals LP, USA

[P1.84]

Development of a flexible synthesis of alkynyl ethers and a facile, low temperature [3,3]-sigmatropic rearrangement of allyl and benzyl alkynyl ethers
T.G. Minehan*, A.A. Tudjarian, J. Sosa, S. Rab, N. Vidar; California State University at Northridge, USA

[P1.85]

Novel synthesis of tetrasubstituted pyrrole by regioselective 1,3-dipolar cycloaddition and spontaneous decarboxylation
Y. Kim*, J. Kim, M.Y. Cha, S.B. Park; Seoul National University, South Korea

[P1.86]

Electrophilic carbonyl additions: A route to alpha-haloacylals and other geminal bis-electrophiles
D.H. Murray*;  Andrews University, USA

[P1.87]

Electrogenerated base/anion promoted synthesis of new rhodanine derivatives
K. Tissaoui, N. Raouafi*, K. Boujlel;  Tunis El-Manar University, Tunisia

[P1.88]

A novel isocyanide-based four component reaction: A facile synthesis of fully substitute 3,4-dihydrocoumarin derivatives
A.H. Rezayan*¹, A. Shaabani², E. Soleimani², A. Sarvary²; ¹Marand Islamic Azad University, Iran, ²Shahid Beheshti University, Iran

[P1.89]

Bifunctional polyethylene glycol (peg) linkers for chemoselective ligation
M.K. Urlam*, E.L. Chaikof; Emory University School of Medicine, USA

[P1.90]

Highly efficient aminocarbonylation via the introduction of carbon monoxide into a pressurized continuous-flow reactor
K. Niesz*, C. Csajági, B. Borcsek, Z. Bajkó, L. Ürge, F. Darvas; ThalesNano Inc., Hungary

[P1.91]

[Et3N(CH2)4SO3H]+[OTS]- as an efficient catalyst for chemoselective thioacetalization of aldehydes under solvent-free conditions
A.R. Hajipour*;  IUT and UW-Madison, Iran

[P1.92]

Chemical modification of proteins
G.J.L. Bernardes*, J.M. Chalker, B.G. Davis;  University of Oxford, UK

[P1.93]

New nordihydroguaiaretic acid (NDGA) derivatives as anti-HIV agents
M.-H. Hsu*¹,², R.C.C. Huang², J.R. Hwu¹; ¹National Tsing Hua University, Taiwan, ²The Johns Hopkins University, USA

[P1.94]

Design, synthesis and validation of Mannose-Pepstatin tools to study the role of Aspartic proteinases in antigen processing
E.A. Raiber*, T. Boyle, C. Tulone, B. Chain, A.B. Tabor; University College of London, UK

[P1.95]

Preparation and evaluation of small molecule binding to trinucleotide repeat d(GAA)n
H. He*, M. Hagihara, K. Nakatani; Osaka University, Japan

[P1.96]

The synthesis of novel 2’,3’-dideoxy-C-nucleosides as potential antiviral agents
N. Pouli*¹, P. Marakos¹, T. Tite¹, N. Lougiakis¹, J. Balzarini²;  ¹University of Athens, Greece, ²K.U.Leuven, Belgium

[P1.97]

QSPR analysis of logP(O/W) of n-arylhydroxamic acids
R. Pande*, R.P. Rajwade;  Pt. Ravishankar Shukla University, India

[P1.98]

The new unsaturated acyclic C-5 pyrimidine nucleoside analogues: Synthesis, cytostatic and anti-HIV evaluations
T. Gazivoda*¹, S. Raic-Malic¹, S. Kraljevic-Pavelic², K. Pavelic², J. Balzarini³, M. Mintas¹;  ¹Zagreb University, Croatia, ²Rudjer Boskovic Institute, Croatia, ³Katholieke Universiteit Leuven, Belgium

[P1.99]

Structure-based design and subsequent optimization of 2-Tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase
D.A. Cogan*¹, D.R. Goldberg¹, M.H. Hao¹, R. Kroe¹, N. Moss¹, C.P. Pargellis¹;  ¹Boehringer Ingelheim Pharmaceuticals, Inc., USA, ²AMRI, USA

[P1.100]

Pyrazinoindole inhibitors of MAPKAP-K2: A potential treatment for chronic inflammatory diseases
C. Miller*;  Boehringer Ingelheim Pharmaceuticals, USA

[P1.101]

Synthesis of valproic acid derivatives and their evaluation for anticonvulsant activity
N. Upmanyu*¹, S.P. Gupta², R.D. Gupta¹, J.K. Grover³, P. Mishra¹;  ¹DDr H. S. Gour Vishwavidayalaya, India, ²Rajiv Gandhi Institute of Pharmacy, India, ³All India Institute of Medical Sciences, India

[P1.102]

Rational design of novel dual action neuronal nitric oxide synthase inhibitors with 5HT 1D/1B agonism for the treatment of migraine pain
S. Annedi*¹, J. Ramnauth¹, J. Patman¹, P. Renton¹, S. Maddaford¹, S. Rakhit¹; ¹NeurAxon Inc., Canada, ²University of Arizona, USA, ³Scripps Research Institute, USA, ⁴Bioopta Ltd, UK, ⁵NoAB Biodiscoveries Inc., Canada

[P1.103]

Synthesis and evaluation of novel nitric oxide releasing derivatives of salicylamide
N. Mehta*, T.R. Bhardwaj, M. Kumar, N. Dhingra; Panjab University, India

[P1.104]

A novel detection method for the explosive TATP
S.M. Malashikhin*, N.S. Finney; University of Zurich, Switzerland

[P1.105]

Heteroditopic fluorescent receptor for recognition of iodide
D.O. Jang, N. Singh, H.J. Jung*; Yonsei University, South Korea

[P1.106]

Excited particles in metastable states the intermediate products of chain reactions as the possible reasons of bifurcations in reaction systems
G.N. Sargsyan;  Academy of Science of Armenia, Armenia

[P1.107]

Reactions of N-acryloyloxyethyltetrabromophthalimide polymers with hydroxy and amino compounds
A. Khalil;  Benha University, Egypt

[P1.108]

2-amino-5-sulfanyl-1-1,3,4-thidiazoles: A novel series of anti-inflammatory and analgesic agents
J. Sainy¹*, G.P.Mishra¹, R.Sharma¹, S.C. Chaturvedi²; ¹School of Pharmacy, India, ²College of Pharmacy, India

[P1.109]

Synthesis of 9-deazaguanosine derivatives as potential anti-viral agents
C. Pierra¹* M. Hamann,¹ J.-P. Sommadossi,² A. Giulia Loi,³ M. Liuzzi,³ R. Storer⁴, G. Gosselin¹;
¹Idenix Medicinal Chemistry Laboratory, France, ²Idenix Pharmaceuticals Inc., USA, ³Laboratorio Cooperativo Idenix-Università di Cagliari, Italy, ⁴Summit plc, UK

[P1.110]

Polymeric organoiron compounds with cancinostatic properties (branched Hydrazone linkers)
D. Nkazi*, E.W. Neuse; Wits University, South Africa

[P1.111]

Green Photochemistry: Sun-induced aromatic nucleophilic substitution of alkoxy groups by alkylamines. Transformation of benzocrown ethers into aza-analogs
A.V. Samoshin, A.H. Franz, V. V. Samoshin*; University of the Pacific, USA

[P1.112]

trans-2-Aminocyclohexanol as a pH-Sensitive Conformational Switch in Lipid Amphiphiles
B. Brazdova  N.  Zhang, V.V. Samoshin*, X. Guo*; University of the Pacific, USA

Poster session two

[P2.1]

Towards the total synthesis of oxazolomycin and neooxazolomycin
R.J.K.T. Taylor*, R.B. Bastin; University of York, UK

[P2.2]

Convenient synthesis of sympathomimetics based on phenyl ethyl amine by anchimeric assistance in 1-phenyl-2-chloroethyl thiol
O.A. Awofisayo*, S.O. Awofisayo; University of Uyo, Nigeria

[P2.3]

Facile and efficient palladium-catalyzed dearomatization of benzylic chlorides with allenyltributyltin
B. Peng¹, S. Lu¹, M. Bao*¹, Y. Yamamoto²;  ¹Dalian University of Technology, China, ²Tohoku University, Japan

[P2.4]

Synthesis of some new [1,2,4]-triazole-3-thiones
A. Rifati*, S. Govori, O. Leci, V. Kalaj, H. Ibrahimi, A. Bytyqi; University of Prishtina, Kosovo

[P2.5]

Synthesis of mannose and glucose derivatives for protein stabilisation studies
E. Lourenço¹, C.D. Maycock¹,², M.R. Ventura*¹; ¹Nova de Lisboa, Portugal, ²Universidade de Lisboa, Portugal

[P2.6]

“On-water” synthesis: Application for the synthesis of pharmaceuticals
B. Pujala*, A.K. Chakraborti; National Institute of Pharmaceutical Educational Research (NIPER), India

[P2.7]

Expedient single step mono N-tert-butylation of amines at ambient temperature
S.V. Chankeshwara*, A.K. Chakraborti; National Institute of Pharmaceutical Educational Research (NIPER), India

[P2.8]

Nonenzymic polycyclization of analogues of oxidosqualene with preformed C-ring
P.J. De Clercq¹, J.M. Winne*¹, M. Milanesio², P. Pattison³, D. Viterbo²; ¹Ghent University, Belgium, ²Università del Piemonte Orientale A. Avogadro, Italy, ³EPFL Lausanne, Switzerland

[P2.9]

“On-water” synthesis of 1,3-diaryl-2,3-dihydro-1,5-benzothiazepines
G. Sharma, R. Kumar, A.K. Chakraborti*;  Nationall Institute Pharmaceutical Education Reseserve (NIPER), India

[P2.10]

Molecular rearrangement of 9b-hydroxy-imidazo[4,5-C]quinoline-2,4-diones – an easy pathway to spiroindolinones
A. Klasek*¹, A. Lycka², I. Miksik³;  ¹Tomas Bata University, Czech Republic, ²Research Institute for Organic Syntheses, Czech Republic, ³Academy of Sciences of the Czech Republic, Czech Republic

[P2.11]

Preparation of thiazolo[5,4-C]quinoline-2,4-diones and thiazolo[3,4-C]quinazoline-3,5-diones
V. Mrkvicka*¹, A. Klasek¹, J. Kosmrlj²; ¹Tomas Bata University, Czech Republic, ²University of Ljubljana, Slovenia

[P2.12]

The synthesis of α-amino-phosphonates by catalytic stereoselective Michael addition
Tr.S. Pham*¹, Zs. Jászay¹, P. Bakó¹, I. Petneházy¹, L. Tőke²;  ¹Budapest University of Technology and Economics, Hungary, ²Organic Chemical Technology Research Group of the Hungarian Academy of Sciences, Hungary

[P2.13]

Studies on the resolution of 2-halo-4-hydroxycycloalkenones via stereoselective formation of 2-oxoazabicyclo-[x.1.0]-alkanes
C.D. Maycock*, P. Rodrigues;  Universidade Nova de Lisboa, Portugal

[P2.14]

Highly active catalysts for the Staudinger reaction
R. Wilhelm*, O. Sereda;  Clausthal University of Technology, Germany

[P2.15]

Total synthesis of (-)-histrionicotoxin 285A
J.M. Macdonald*¹, J.H. Ryan¹, S. Saubern¹, A.B. Holmes¹,²;  ¹CSIRO, Australia, ²University of Melbourne, Australia

[P2.16]

One-pot synthesis of some new spiro derivatives of 2-pyrazolines at C3 position
M. Shaabanzadeh*;  Islamic Azad University, Damghan Branch, Iran

[P2.17]

Highly efficient carbon-carbon bond forming reactions catalyzed by bis(oxazolinyl)phenyl-Pd(II) complexes
T.T. Takemoto, K.P. Phomkeona, K.S. Shibatomi, S.I. Iwasa*; Toyohashi University of Technology, Japan

[P2.18]

Enantioselective allylation of aldehydes employing beta-amido allylstannanes catalyzed by chiral in(OTf)3/i-Pr-pybox complexes
T. Suzuki*, T. Sengoku, M. Takahashi, H. Yoda; Shizuoka University, Japan

[P2.19]

Synthesis, structure and reactivity of sugar-derived phosphorusylides
N. Sahabo*, N. Karodia; University of Bradford, UK

[P2.20]

A novel and highly versatile approach to C- and c-aza-nucleosides
J. Rousseau*¹,², P. Redpath¹,², M.E Migaud¹,²; ¹Queen's University, UK, ²GlaxoSmithKline, UK

[P2.21]

A Wacker - Cook synthesis of isoflavones
E.H. Granados- Covarrubias*, L.A. Maldonado Graniel; UNAM, Mexico

[P2.22]

Discovery of an RNaseA mimic using synthetic SELEX
D.M. Perrin,* Y. Roupioz, L. Lermer, R.Ting, J. Thomas, J. May, M. Hollenstein; University of British Columbia, Canada

[P2.23]

The telescoped intramolecular Michael / Olefination (TIMO) approach to α-alkylidene-γ-butyrolactones: Synthesis of (+)-paeonilactone b
M.G. Edwards*, M.N. Kenworthy, R.R.A. Kitson, M.S. Scott, R.J.K. Taylor; University of York, UK

[P2.24]

Synthesis of stable Acetyl ADPR analogues
IM Messsina*, MD Dvorakova; Queen's University, UK

[P2.25]

Carbohydrate derivatives as building blocks in organic synthesis
M.M. Andrade, M.T. Barros*, K.T. Petrova, R.M. Pinto, P.M. Correia-da-Silva; Universidade Nova de Lisboa, Portugal

[P2.26]

Mechanistic study probing β-stereoselectivity of 4,6-O-benzylidine acetal-protected mannosyl iodide
R.A. Davis*, M.H. El-Badri, D. Willenbring, D.J. Tantillo, J. Gervay-Hague; University of California at Davis, USA

[P2.27]

Application of phase transfer catalyst: One-pot synthesis of novel 7 to 9 membered fused tricyclicquinolones and quinolinium salts
P. Paira, A. Hazra, K. Sahu, S. Banerjee, N.B. Mondal*, N.P. Sahu; Indian Institute of Chemical Biology, India

[P2.28]

Progress towards the total synthesis of daphnicyclidin C
D. Williams, P. Nag*; Indiana University, USA

[P2.29]

Efficient synthesis of (1H-Pyrrole-2-carbonyl)glycylglycine alkyl esters
X.C. Zeng*, G.H. Tang, D.D. Li, Y.Z. Cen; Jinan University, China

[P2.30]

Kilogram-synthesis and an improved synthesis of a selective serotonin re-uptake inhibitor
C.-K. Chen*, R. Anthes, O. Bello, S. Benoit, E. Corbett, R.M. Corbett et al.; Bristol-Myers Squibb Co., USA

[P2.31]

Efficient one-pot preparation of pyrazinothienopyrimidines and bis(pyrazinothienopyrimidines) based on an Aza–Wittig/electrocyclic ring closure strategy
G. Blanco-Díaz*, A. Fernández, C. Peinador, J.M. Quintela; University of A Coruña, Spain

[P2.32]

Artificial poteases selective for soluble oligomers of amyloid beta peptide or human islet amyloid polypeptide
W.S. Chei*, T.Y. Lee, J. Suh; Seoul National University, South Korea

[P2.33]

Withdrawn

[P2.34]

Regioespecific microwave-assisted synthesis of (rs)-6-substituted-7- or 9-(2,3-dihydro-5h-1,4-benzodioxepin-3-yl)-7h- or -9h-purines: Anti-breast cancer activity
J.M. Campos*, M.A. Gallo, A. Conejo-García, M.C. Núñez, A. Espinosa; University of Granada, Spain

[P2.35]

Synthesis and applications of O6-benzylguanine-BAPTA probes for studying calcium signalling in living cells
I.R. Correa Jr.*, M. Bannwarth, A. Ruggiu, K. Johnsson; EPFL, Switzerland

[P2.36]

Synthesis, cytotoxicity and DNA binding studies of novel bisnaphthalimidopropyl polyamine derivatives (BNIPPs)
G.A. Barron*¹, G. Bermano², A. Gordon¹, P. Kong Thoo Lin¹; ¹Robert Gordon University, UK, ²Centre of Obesity Research and Epidemiology (CORE), UK

[P2.37]

Towards ion pair exchange ligand-receptor engineering of protein kinase B’s Pleckstrin homology domain
S.J. Cooper*, P.R.J. Gaffney, D. Mann;  Imperial College London, UK

[P2.38]

Investigation of the role of diacylglycerol in nuclear envelope assembly using synthetic fluorescent phosphatidylinositol probes
T.C. Huynh*¹,², P.R.J. Gaffney¹, B. Larijani²;  ¹Imperial College London, UK, ²Cancer Research UK, UK

[P2.39]

Preparation of a site-specific biotin-albumin conjugate
K. Paal*, S. Mavilla; University of Ontario Institute of Technology, Canada

[P2.40]

Scaffolds for antibody-based cancer therapy by site-specific conjugation and ligation through click chemistry
J.G. Go*¹, J.P. Saludes¹, A. Natarajan², S.J. DeNardo², J. Gervay-Hague¹; ¹University of California at Davis, USA, ²DUC Davis Medical Center, USA

[P2.41]

Chemoenzymatic method for site specific fluorescent labeling of tubulin
Ö. Dilek*, A. Banerjee, S. Bane; State University of New York at Binghamton, USA

[P2.42]

Synthesis of vanchrobactin analogue-antibiotic quinolone conjugates used as Trojan horse against vibriosis
M. Larrosa*, R. G. Soengas, J. Rodríguez, C. Jiménez;  University of A Coruña, Spain

[P2.43]

In vitro dissolution study in multimedia in analytical development by high performance liquid chromatography of an anti-cancer drug Letrazole HCl in their pharmaceutical dosage form
T. Barot*, P. Patel; M.G.Sciences Institute, India

[P2.44]

Synthesis and anti-diabetic studies of few indole derivatives
V.A. Chatpalliwar*, S.S. Tangadpalliwar, S.C. Khadse, R.R. Patil, S.J. Surana; R. C. Patel College of Pharmacy, India

[P2.45]

Synthesis and pharmacological screening of 5-(Substituted Benzyl)-3- phenyl-1, 6-dihydro-6-pyridazinones
S. Drabu¹, A. Husain², N. Kumar*²; ¹MSIP, India, ²JAMIA HAMDARD, India

[P2.46]

Aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90)
T. Ganesh*, J. Min, P. Thepchatri; Emory University, USA

[P2.47]

Piperazino-derivatives of dibenzoxepin and dibenzothiepin for anti-psychotic activity
R.R. Patil¹, S.C. Khadse¹, V.A. Chatpalliwar¹, S.B. Wagh², R.A. Fursule¹, S.J. Sirana*¹; ¹R. C. Patel College of Pharmacy, India, ²N.D.M.V.P.S.College of Pharmacy, India

[P2.48]

Allosteric inhibition of [125I] ET-1 binding to ETA receptors by aldoxime and hydroxamic acid derivatives
M. Ahmed*¹, S. Nencetti², M. Mazzoni², F. Porchia², F. Antonelli², A. Lapucci²; ¹Arab Medical Sciences University, Libya, ²University of Pisa, Italy

[P2.49]

Side chain modified 8-aminoquiolines as potential antiprotozoal and antimicrobial agents
K. Kaur*, R. Jain;  National Institute of Pharmaceutical Education and Research, India

[P2.50]

Discovery and optimization of diamine analogs as potent inhibitors of leukotriene A4 hydrolase
A. Cleve*¹, S. Jaroch¹, T. Kirkland², G. Phillips², J. Parkinson², W.J. Guilford²;  ¹Bayer HealthCare AG, Germany, ²Berlex Biosciences, USA

[P2.51]

Parallel synthesis of GPCR ligands taking advantage of novel click chemistry derived resins
S. Loeber*, L. Leeb, P. Gmeiner; University Erlangen-Nuernberg, Germany

[P2.52]

Natural product-based approach for the design of chiral gem-dimethylcyclopropane derivatives
K. Gajcy¹, T. Librowski², S. Lochyński¹; ¹ Wrocław University of Technology, Poland, ²Jagiellonian University, Poland

[P2.53]

Synthesis and biological evaluation of curcumin pyrazoles as new therapeutic agents in inflammatory bowel disease (IBD)
L. Bouissane¹, M.P. Cabildo¹, M.P. Cornago¹, R.M. Claramunt*¹, J. Elguero², C. Medina³;  ¹UNED, Spain, ²CSIC, Spain, ³Trinity College Dublin, Ireland

[P2.54]

Application of oxime-based peptide libraries for Tsg101 ligand optimization: Towards a new class of anti-HIV-1 therapeutics
F. Liu*¹, A.G. Stephen², A.A. Waheed¹, E.O. Freed¹, R.J. Fisher², T.R. Burke¹; ¹NIC Frederick, NIH, USA, ²SAIC-Frederick, Inc., USA

[P2.55]

Modulators of the nicotinic alpha4beta2 receptor for the treatment of neuropathic pain
S.K. Springer*, B.K. Albrecht, A. Boezio, J.C. Harmange, K. Woodin, S.I. McDonough;  Amgen, Inc., USA

[P2.56]

Efficient synthesis of various drug-like heterocycles through cyclic iminium intermediates
S.B. Park*, S.-C. Lee, Y.J. Kim, M. Koh;  Seoul National University, South Korea

[P2.57]

Synthesis and biological evaluation of new 5-phenyl-1,2,4-thiadiazole derivatives as NOS inhibitors
M.D. Carrion, E. Camacho, M.A. Gallo, A. Espinosa, A. Entrena*;  University of Granada, Spain

[P2.58]

Evaluation of lipophilicity of N-arylsubstituted hydroxamic acids by RP-HPLC and 3d-QSPR approach using the K-nearest neighbor method
A. Dixit, R.P. Rajwade, R. Pande*; Pt. Ravishankar Shukla University, India

[P2.59]

Synthesis of 2, 5 disubstituted 1, 3, 4 oxadiazole and thiadiazole - some new nitrogen mustard as a possible anticancer agent
R.A. Fursule*¹, R.L. Bakal¹, A.M. Manikrao²; ¹H. R. Patel Women's College of Pharmacy, India, ²SGSPS Institute of Pharmacy, India

[P2.60]

PEGylation of dendrimers: A new synthetic approach
P. Trivedi*¹, S.P. Gautam¹, H. Khambete¹, C. Karthikeyan¹, S. Ramteke¹, N.S. Hari Narayana Moorthy¹;  ¹Rajiv Gandhi Technological University, India

[P2.61]

Synthesis of chiral long chain 1,2-diamines and study of their effect on the enzymes involved in the endocannabinoid system
V. Magrioti¹, G. Naxakis¹, D. Hadjipavlou-Litina², A. Makriyannis³, G. Kokotos*¹;  ¹University of Athens, Greece, ²University of Thessaloniki, Greece, ³Northeastern University, USA

[P2.62]

Dimeric dopamine receptor ligands – synthesis and biological properties
H. Huebner*, P. Gmeiner;  FAU Erlangen, Germany

[P2.63]

Preparation of novel 1-trifluoromethyl-6-(dialkylamino)ethoxy-1,2-diphenylindenes and their biological activity
I.H. Jeong¹, B.T. Kim², Y.K. Min², J.H. Choi*¹,  ¹Yonsei University, South Korea, ²Korea Research Institute of Chemical Technology, South Korea

[P2.64]

Synthesis of neutral CMP-sialic acid analogs as polysialyltransferase inhibitors
J.H. Wong*, D. Nakata, F.A. Troy, II.; University of California at Davis, USA

[P2.65]

The synthesis and binding modes of benzimidazole derivatives
L. Winfield*¹, D. Smith²;  ¹Spelman College, USA, ²Whitman College, USA

[P2.66]

Biogenetic route study in natural alkaloid possibly formed via Diels-Alder reaction
J. Ren, Y.T. Di, X.J. Hao, S.P. Jiang, H.J. Zhu*;  Kunming Institute of Botany, China

[P2.67]

Alzheimer’s disease: A better lead identification by binding free energy calculations for tacrine
S. Vengurlekar¹, R. Sharma¹, P. Trivedi²*; ¹Devi Ahilya University, India, ²Rajiv Gandhi Proudyogiki Vishwavidyalaya, India

[P2.68]

QSAR models for predicting enzymatic hydrolysis of new chemical entities as an effective tool in “soft-drug” design
I. Massarelli, M. Macchia, F. Minutolo, G. Prota, A.M. Bianucci*; University of Pisa, Italy

[P2.69]

Synthetic scope and mechanistic origin of a new series of exo-selective intermolecular diels-alder reactions
Y.-H. Lam*¹, P.H.-Y. Cheong², J.M. Blasco Mata¹, S.J. Stanway³, V. Gouverneur¹, K.N. Houk²;  ¹University of Oxford, UK, ²University of California at Los Angeles, USA, ³GlaxoSmithKline, UK

[P2.70]

Chiral NMR solvating agents for the determination of enantiomeric excess and assignment of absolute configuration of cyanohydrins
L.S. Moon, R.S. Jolly*; Institute of Microbial Technology, India

[P2.71]

Potential novel copper complex: A product formed through reaction of Cu2(xC6H4COO)4 and ketone in acidic condition
M.I. Mohamadin*, N. Abdullah; University of  Malaya, Malaysia

[P2.72]

Easy synthesis of novel and strained thietanoquinolines and thiophenoquinolines
M.J. Haddadin*¹, C. Nachef¹, H. Kisserwan¹, M.J. Kurth¹, J. Fettinger¹;  ¹American University of Beirut, Lebanon, ²University of California at Davis, USA

[P2.73]

Synthesis of optically active conjugated polymers with azobenzene moieties from achiral monomers in cholesteric solvent
R. Ohta*, F. Togashi, H. Goto;  University of Tsukuba, Japan

[P2.74]

Secondary structure mimetics as inhibitors of protein/protein interactions
G.R. Marshall*¹, Y. Che²;  ¹Washington University, USA, ²National Institutes of Health, USA

[P2.75]

Role of the hydrophobicity of the alkyl substituent in the π-donor heteroatom on the thermodynamic and kinetic acidity of Fischer thicarbene complexes
D.M. Andrada*, M.E. Zoloff Michoff, Al.M. Granados, R.M. Hoyos de Rossi; Ciudad Universitaria, Argentina

[P2.76]

Synthesis and crystal structure of some 3,5-pyrazolidinediones
S.A.M. Metwally*¹, M.I. Abdel Moneim¹, Y.A. Elossely¹, R.I. Awad¹, A. Linden², K. Abou-Hadeed²; ¹Assiut University, Egypt, ²TH-Zurich, Switzerland

[P2.77]

A novel approach to the rapid, one step labelling of biomolecules for PET: Boronic acids as captors of aqueous 18F-fluoride
D.M. Perrin*¹,², R. Ting¹,², C. Harwig¹,², U. auf dem Keller¹,², C.M. Overall¹,², M.J. Adam¹,², T.J. Ruth¹,²; ¹ University of British Columbia, Canada, ²TRIUMF, Canada

[P2.78]

Cope rearrangements versus ring closure in the flash vacuum pyrolysis of acyclic dienes and enynes
E.L. Moyano¹, N.M. Ceballos*¹, I. Iwataki², G.I. Yranzo¹;  ¹Universidad Nacional de Córdoba, Argentina, ²Nippon Soda Co., USA

[P2.79]

A novel three- component reaction for the diastereoselective synthesis of R and S (11bS)-dimethyl 2, 11b-dihydro-2-(3-nitrophenyl)-[1, 3] oxazino[2, 3-a]-isoquinoline-3, 4-dicarboxylate and (11bs)- dimethyl 2, 11b-dihydro-2-(5-nitrofuran-2-yl)-[1, 3] oxazino[2, 3-a]-isoquinoline-3, 4-dicarboxylate Via 1, 4-dipolar cycloaddition
M. Asnaashari Isfahani*, F. Ziayi Rad;  Islamic Azad University, Iran

[P2.80]

A one-pot synthesis of heterocyclic compounds, through the reaction of methylpyruvate and bebzealdehyd or furfural derivatives
M. Asnaashari Isfahani*¹, I. Yavari², A. Rekabdar¹;  ¹Islamic Azad University, Iran, ²University of Tarbiat Modarres, Iran

[P2.81]

Chiral ammonium hypophosphites: Enantioselective synthesis of amines
S.Yoon Kim¹*, W.Chavasiri², D.O.Jang¹; ¹Yonsei University, Korea, ²Chulalongkorn University, Thailand

[P2.82]

Organocatalytic asymmetric transfer hydrogenation of α,β-unsaturated ketones and nitroolefins
N.J.A. Martin*, B. List;  Max-Planck-Institut für Kohlenforschung, Germany

[P2.83]

Synthesis of well-defined dendronized polymers having chiral ephedrine moieties and their applications as reagents for highly enantioselective addition of dialkylzinc reagents to aldehydes and imines
A. El-Shehawy*¹, K. Sugiyama², A. Hirao²; ¹Kafr El-Sheikh University, Egypt, ²Tokyo Institute of Technology, Japan

[P2.84]

A facile and regioselective synthesis of partially benzoylated sucralose suitable for chain extension at position O-6
S.E. Soliman, R.W. Bassily, R.I. El-Sokkary*, M.A. Nashed;  Alexandria University, Egypt

[P2.85]

Reactions of benzoselenophenones, benzisoselenazolones and related selenaheterocycles with nucleophiles
R. Lisiak*, J. Mlochowski; Wroclaw University of Technology, Poland

[P2.86]

(mu-Hydroxo)-platinum complex-catalyzed enantioselective aldol reaction for anti-propionates
S.-I. Kiyooka*, S. Matsumoto;  Kochi University, Japan

[P2.87]

Reactivity of the insecticide fenitrothion towards O and N nucleophiles
N.M. Rougier*, R.V. Vico, R.H. de Rossi, E.I. Buján; Universidad Nacional de Córdoba, Argentina

[P2.88]

Synthesis and biological evaluation of anticancer β-lactams
B.K. Banik*¹, I. Banik², F.F. Becker²;  ¹University of Texas-Pan American, USA, ²University of Texas M. D. Anderson Cancer, USA

[P2.89]

A safe, convenient and efficient method for the preparation of heterocyclic n-oxides using urea•hydrogen peroxide
D. Rong*, R. Wheelhouse;  University of Bradford, UK

[P2.90]

Synthesis of ureas based on bifunctionalized limonenes and study of their catalytic activity
D. Tringidou, C.G. Kokotos, G. Kokotos*;  University of Athens, Greece

[P2.91]

Analysis of residual solvents in health functional food by head space sampling coupled with gas chromatography-mass spectrometry
H.-M. Lee*, H.Y. Kim, Y.M. Jang;  KFDA, South Korea

[P2.92]

The use of a novel flow reactor system as a viable alternative to microwave assisted organic synthesis
I. Kovács*, L. Ürge, F. Darvas; ThalesNano Inc., Hungary

[P2.93]

The fully automated optimization of selective hydrogenation reactions using catalyst screening and temperature
R. Jones*, I. Kovács, F. Darvas, L. Ürge;  ThalesNano Inc., Hungary

[P2.94]

Regioselective catenation of dinuclear palladium metallocycles induced by pi-pi interactions
V. Blanco*, D. Abella, E. Pía, C. Peinador, J.M. Quintela; University of A Coruña, Spain

[P2.95]

Synthesis of orthogonally protected lanthionine, and the solid phase peptide synthesis of an analogue of nisin rings A and B
D.C. Nicolau*¹,², P. Gaffney¹, P. Driscoll², A.B. Alethea²,  ¹Imperial College London, UK, ²University College London, UK

[P2.96]

End functionalisation of glycosaminoglycans: Methods and applications
B. Blaum, E. Gemma, A.N. Hulme*, L. Jin, O. Meyer, D. Uhrin; University of Edinburgh, UK

[P2.97]

HPLC profile and structural determination of defensive secretions of Cuban endemic millipede in searching for new bioactive compounds
J.A. Mesa Diaz*, J.E. Tacoronte Morales; Centre of Engineering and Chemical Researches, Cuba

[P2.98]

Synthesis and in-vitro antimycobacterial activity of novel amino pyrimidine derivatives
M. Ashraf Ali*², M. Shahar Yar¹;  ¹Jamia Hamdard University, India, ²Alwar Pharmacy College, India

[P2.99]

Self organizing molecular field analysis on antitumor activity of N-arylsubstituted hydroxamic acids
R.P. Rajwade*, R. Pande;  Pt. Ravishankar Shukla University, India

[P2.100]

Concise synthesis and potent antioxidative activity of novel trans-stilbene derivatives
M. Jung¹, E. Lim*¹, J.-C. Jung¹, S. Oh¹, Y. Lee¹, J.-M. Kanf¹; ¹Yonsei University, South Korea, ²Ewha Womans's University, South Korea

[P2.101]

Asymmetric hydrogenation in green reaction media using metal/dipyridinylphosphine complex
K. H. Lam¹, S. H. Chan¹*, L. Xu, Q Fan², A. S.C.Chan¹; ¹Hong Kong Polytechnic University, Hong Kong, ²Chinese Academy of Sciences, China

[P2.102]

Conventional and solid-phase microwave syntheses of hydroxypyran-4-one and hydroxypyridin-4-one analogues and their tyrosinase inhibitory activity
E.A. Cioffi*, E. Shimazaki, C. Stanberry, S. Bokatzian-Johnson; University of South Alabama, USA

[P2.103]

Design and synthesis of novel small molecule modulators for specific functional regulation of orphan nuclear receptor, ERRg
Y. Kim, M. Koh*, S.B. Park; Seoul National University, South Korea

[P2.104]

Synthesis and biological screening of benzopyrano-heterocyclic focused library for the development of novel therapeutic agents of osteoporosis
M. Zhu*, S.H. Kim, Y.G. Min, S.B. Park;  Seoul National University, South Korea, ²Korea Research Institute of Chemical Technology, South Korea

[P2.105]

Identification of antimicrobial phytochemicals from Artemisia iwayomogi and Chrysanthemum zawadskii
H.S. Chung*¹, S.W. Shin¹, E.S. Kim¹, Y.H. Lee², M.Y. Lee², K.U. Lee²;  ¹DukSung Women's University, South Korea, ²Seoul Women's University, South Korea

[P2.106]

Pharmacological actions of (+)-dihydroperfamine and its derivatives
A.J. Al-Rehaily*, M.S. Ahmed, K.E.H. ELTahir; King Saud University, Saudi Arabia

[P2.107]

Structurally homogeneous cyclic tetrapeptides as potent HDAC inhibitors
A. Montero*, J.M. Beierle, C.A. Olsen, M.R. Ghadiri; The Scripps Research Institute, USA

[P2.108]

Theoretical models for classification as cardioprotective agents of mitochondrial-KATP channel openers (mito-KCOs) possessing the 4-spiro-substituted benzopyranic structure
A. Coi, A.M. Bianucci*, V. Calderone, L. Testai, M. Manganaro, S. Rapposelli; University of Pisa, Italy

[P2.109]

A search for optimal fastness/accuracy compromises in developing predictive models for estimating CYP2D6 inhibition properties of drug candidates
M. Saraceno, A.M. Bianucci*; University of Pisa, Italy

[P2.110]

trans-2-Aminocyclohexanols as pH-triggered molecular switches
B. Brazdova , Y. S. Wong, A. Samoshin , N. Zhang , A. Franz , X. Guo, V.V. Samoshin*;  University of the Pacific, USA

[P2.111]

Novel inhibitors for fungal glycosidases
B.Brazdova, N.S. Tan*, N.M. Samoshina, V.V. Samoshin*; University of the Pacific, USA

[P2.112]

Comparative study of colorimetric methods for analysis of water-soluble and immobilized proteins and peptides
 N.M. Samoshina, V.V. Samoshin*; University of the Pacific, USA