Program

Tuesday 22 July 2008

15:00 – 18.00

Registration and Poster Set-up

Wednesday 23 July 2008

07.30

Registration

09:00

Opening presentation

09:10

Biology oriented synthesis
Herbert Waldmann, Max-Plank Institute, Germany

09:50

Chemo-allosteric control of proteolysis
James Wells, University of California, San Francisco, USA

11:30

Total synthesis of natural products of biological intrigue
Robert Williams, Colorado State University, USA

13:40

Molecular diversity and catalysis
Donald Hilvert, ETH Zurich, Switzerland

14:20

Building molecules to image tumors, clots, and atherosclerotic plaques in vivo
Roger Tsien, University of California, San Diego, USA

16:00

Tetrahedron Young Investigator Award Winner 2008: Organic Synthesis
C-H functionalization as an enabling technology for fine chemicals synthesis
Justin DuBois, Stanford University, USA

16:40

Computer-aided drug lead generation and optimization
William Jorgensen, Yale University, USA

17:20

End of Day 1

Thursday 24 July 2008

09:00

Bcl-2 family inhibitors for the treatment of cancer
Stephen Fesik, Abbott Laboratories, USA

09:40

Structural basis of acridine drug recognition by a human telomeric DNA quadruplex
Stephen Neidle, University of London, UK

11:20

Evolution of chemistry: Examples in our labs
Tohru Fukuyama, University of Tokyo, Japan

13:30

Chemical genetic analysis of protein kinase cascades
Kevan Shokat, University of California, San Francisco, USA

14:10

Supramolecular chemistry with DNA
Hanadi Sleiman, McGill University, Canada

15:50

Tetrahedron Young Investigator Award Winner 2008: Biomedicinal Chemistry
Mapping biochemical patchways in human diseases by activity based proteomics and metabolomics
Ben Cravatt, Scripps, USA

14:30

DNA charge transport in chemistry and biology
Jacqueline Barton, California Institute of Technology, USA

17:10

End of Day 2

17:30

Optional Gala Dinner Cruise

Friday 25 July 2008

09:00

It's better to be lucky than smart: A realistic look at rational drug discovery
Paul J. Reider, Amgen (retired), USA

09:40

Rapid formation of molecular complexity in natural product synthesis
Erik Sorensen, Princeton University, USA

11:00

Chemical microarrays - massive parallel analysis of proteases, kinases and cells
Mark Bradley, University of Edinburgh, UK

11:40

An expanding genetic code
Peter Schultz, The Scripps Research Institute, USA

12:20 –
12:30

Closing remarks
Award to winners of the Tetrahedron 2008 Poster Awards